Description: Klebsiella pneumonia (KPC) is medically the most important organism of the Klebsiella species.Klebsiella pneumoniae produces a thick capsule layer composed of extracellular polysaccharides protecting the bacterial cells from clearance by innate host immunity during infection. Bacteria producing klebsiella pneumonia carbapenemases (KPCs) are rapidly emerging as a cause of multi drug resistant infections worldwide. It is responsible for a significant proportion of hospital-acquired infections including septicemias, urinary tract infections, pneumonia, and soft tissue infections especially in the immunocompromised hosts. The hands of healthcare workers and the hospitalized patients serve as reservoirs for the transmission of the organism and are responsible for multiple hospital outbreaks. Hence, prevention through implementation of strict infection control guidelines, effective hand washing, proper waste water treatment, proper discarding, use of antibacterial agents and powerful antibiotics which will be affordable, cheap, easily available, nontoxic and with high efficacy which will be the ultimate solution of (MDR) multi drug resistance of this disastrous six fold increasing organism worldwide. The occurrence and vulnerability of significant pathogenic bacteria has been isolated from various hospital’s waste water samples from Karachi Pakistan. Including klebsiella pneumoniae some other different gram negative organisms also observed via healthcare waste.
Socio-Economic Benefits: This research support to decrease the socioeconomic burden of CRE infections and to give ease the clinician to make the suitable strategies of the patient care.
Category: Waste management – Solid Waste management, environmental waste management, Biodegradation, fishery waste management, Marine waste management
Department: Microbiology